The second part of the vaccine, liquid-filled Test Tube (adjuvant), is found in the Incubation Lab on the second floor (2F) of NEST 2. The first part of the vaccine, the culture sample (antigen), is found in Lab 1 on the second floor (2F) of NEST 2. Jill apparently doesn’t need any lab equipment to mix these two items. When you find these two, combine them in your inventory. These two parts are needed to solve the vaccine puzzle. The solution to the vaccine puzzle is mid, high, low.īut for those that might want to know how this puzzle works, let’s start at the beginning with finding the antigen and adjuvant. Any other input will have the temperatures either too hot or too cold. This ensures the temperature across all three sections is in the green zone at about 50. The solution to the vaccine puzzle and temperature control puzzle in NEST 2 is, from left to right: Mid, High, Low. Unless you want to either trial and error your way through those combos or stumble upon the solution, it can be far better to have the answer prepared earlier! Vaccine puzzle solution 
With three buttons each with three different values, there are 27 different possible combinations. The vaccine puzzle in Resident Evil 3 can definitely take a while to figure out.
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